| 发明名称 |
.GAMMA.-SECRETASE IN VITRO SCREENING ASSAY |
| 摘要 |
According to the screening method of the invention substances capable of modulating .gamma.-secretase activity are identified by incubating a source and a substrate of .gamma.-secretase activity with a test substance and detecting a C-terminal fragment released from said substrate.
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| 申请公布号 |
CA2452832(A1) |
申请公布日期 |
2003.01.30 |
| 申请号 |
CA20022452832 |
申请日期 |
2002.06.27 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
KOSTKA, MARKUS;HAASS, CHRISTIAN;DORNER-CIOSSEK, CORNELIA;FUCHS, KLAUS;STEINER, HARALD |
| 分类号 |
G01N33/50;A61K45/00;A61P25/00;A61P25/28;A61P43/00;C12N9/99;C12Q1/02;C12Q1/37;G01N33/15;(IPC1-7):C07K14/47 |
主分类号 |
G01N33/50 |
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