| 摘要 |
225Ac complexes comprising a functionalized polyazamacrocyclic chelant compound of the formula I hereinbelow: wherein: T is G is independently hydrogen or each Q is independently hydrogen, (CHR5)pCO2R or (CHR5)pPO3R6R7 or Q1 is hydrogen, (CHR5)wCO2R or (CHR5)wPO3R6R7; each R is independently hydrogen, benzyl or C1-C4 alkyl; R6 and R7 are independently H, C1-C6 alkyl or (C1-C2 alkyl)phenyl; each R5 is independently hydrogen; C1-C4 alkyl or (C1-C2 alkyl)phenyl; with the proviso that at least two of the sum of Q and Q1 must be other than hydrogen; A is CH, N, C-Br, C-Cl, C-SO3H, C-OR8, C-OR9N+-R10X-, or Z and Z1 independently are CH, N, C-SO3H, N+-R10X-, C-CH2-OR8 or C-C(O)-R11; R8 is H, C1-C5 alkyl, benzyl, or benzyl substituted with at least one R12; R9 is C1-C16 alkylamino; R10 is C1-C16 alkyl, benzyl, or benzyl substituted with at least one R12; R11 is -O-(C1-C3 alkyl), OH or NHR13; R12 is H, NO2, NH2</subscript><
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