发明名称 |
Protein aggregation assays and uses thereof |
摘要 |
This invention features methods for identifying agents that modulate protein aggregation or stabilize protein conformation. Exemplary methods include an in vitro aggregation assay, a native state stabilization assay, a cell-based screening assay, and an animal-based screening assay. These methods can be used to identify agents useful for the treatment of conformational diseases resulting from aggregation of a protein.
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申请公布号 |
US2003022243(A1) |
申请公布日期 |
2003.01.30 |
申请号 |
US20020176809 |
申请日期 |
2002.06.20 |
申请人 |
KONDEJEWSKI LES;CHAKRABARTTY AVIJIT;QI XIAO-FEI;CASHMAN NEIL |
发明人 |
KONDEJEWSKI LES;CHAKRABARTTY AVIJIT;QI XIAO-FEI;CASHMAN NEIL |
分类号 |
G01N33/68;(IPC1-7):G01N33/53;G01N33/567 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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