According to the screening method of the invention substances capable of modulating gamma -secretase activity are identified by incubating a source and a substrate of gamma -secretase activity with a test substance and detecting a C-terminal fragment released from said substrate.
申请公布号
WO03008635(A2)
申请公布日期
2003.01.30
申请号
WO2002EP07095
申请日期
2002.06.27
申请人
BOEHRINGER INGELHEIM PHARMA KG;DORNER-CIOSSEK, CORNELIA;FUCHS, KLAUS;KOSTKA, MARKUS;STEINER, HARALD
发明人
DORNER-CIOSSEK, CORNELIA;FUCHS, KLAUS;HAASS, CHRISTIAN;KOSTKA, MARKUS;STEINER, HARALD
