The present invention is based on the discovery that overexpression of DELTA FosB leads to bone formation and that DELTA FosB expression inhibits adipogenesis. The present invention provides methods of identifying agents that modulate bone formation and adipogenesis. Moreover, the present invention provides methods for identifying genes that are modulated by DELTA FosB, osteogenesis, and adipogenesis.
申请公布号
WO0217858(A3)
申请公布日期
2003.01.30
申请号
WO2001US41890
申请日期
2001.08.28
申请人
YALE UNIVERSITY;BARON, ROLAND, E.;SIMS, NATALIE;SABATAKOS, GEORGIOS;NESTLER, ERIC;CHEN, JINGSHAN;KELZ, MAX
发明人
BARON, ROLAND, E.;SIMS, NATALIE;SABATAKOS, GEORGIOS;NESTLER, ERIC;CHEN, JINGSHAN;KELZ, MAX
