发明名称 CHRYSTAL COMPOSITIONS COMPRISING TOPOISOMERASE I
摘要 This invention relates to crystalline structures of the topoisomerase I and their use in designing new anti-cancer agents and anti-microbial agents. In particular, crystal compositions comprising topoisomerase I, a duplex 22mer DNA and the inhibitors Topotecan, AG260, MJ-II-38 and Hoechst-3342 are disclosed.
申请公布号 WO0240653(A3) 申请公布日期 2003.01.30
申请号 WO2001US43550 申请日期 2001.11.14
申请人 EMERALD BIOSTRUCTURES, INC.;BURGIN, ALEX;HJERRILD, KATHRYN;KIM, HIDONG;STAKER, BART, LEE;STEWART, LANCE;BEHNKE, CRAIG;FEESE, MICHAEL 发明人 BURGIN, ALEX;HJERRILD, KATHRYN;KIM, HIDONG;STAKER, BART, LEE;STEWART, LANCE;BEHNKE, CRAIG;FEESE, MICHAEL
分类号 C12N9/90 主分类号 C12N9/90
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