发明名称 DOLASTATIN 10 DERIVATIVES
摘要 The present invention relates to new compounds of formula I, having an anti-tumor activity, wherein R<1>, R<2>, R<3>, R<4>, R<5> and n are as defined in the description and the claims and pharmaceutical acceptable salts thereof. The present invention concerns also pharmaceutical composition comprising compounds of formula (I), the use of compounds of formula (I) for the preparation of medicaments and process for the preparation of compounds (I).
申请公布号 WO03008378(A1) 申请公布日期 2003.01.30
申请号 WO2002EP07931 申请日期 2002.07.17
申请人 F.HOFFMANN-LA ROCHE AG 发明人 FUJII, TOSHIHIKO;OKADA, TAKEHIRO;TANIGUCHI, MIKIO;WATANABE, FUMIO
分类号 A61K38/00;A61K38/05;A61P35/00;C07D207/08;C07K1/10;C07K5/02;C07K5/027;(IPC1-7):C07D207/08 主分类号 A61K38/00
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