| 摘要 |
The invention provides isolated nucleic acids molecules, designated CDHN nucleic acid molecules, which encode novel cadherin molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CDHN nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a CDHN gene has been introduced or disrupted. The invention still further provides isolated CDHN proteins, fusion proteins, antigenic peptides and anti-CDHN antibodies. Diagnostic methods utilizing compositions of the invention are also provided. |
