| 发明名称 |
E. COLI 0157:H7 C1 ESTERASE INHIBITOR-BINDING PROTEIN STCE AND USES THEREOF |
| 摘要 |
Disclosed is a p0157 plasmid-encoded polypeptide found in <i>E.coli</i> EDL933 and other enterohemorrhagic <i>E.coli</i> that binds to the cleaves C1-esterase inhibitor (stcE). Also disclosed are methods employing the polypeptide for diagnosing and treating colitis or hemolytic uremic syndrome, and methods of detecting potential therapeutics. |
| 申请公布号 |
WO0234918(A3) |
申请公布日期 |
2003.01.30 |
| 申请号 |
WO2001US47719 |
申请日期 |
2001.10.26 |
| 申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
WELCH, RODNEY, A.;LATHEM, WYNDHAM, W. |
| 分类号 |
A61K39/00;C07K14/245;C07K16/12;C12N9/52;C12N15/31;C12Q1/37;C12Q1/68;G01N33/573 |
主分类号 |
A61K39/00 |
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