发明名称 |
Method of monitoring haptotaxis |
摘要 |
The present invention discloses a method of monitoring haptotaxis comprising: providing a device for monitoring haptotaxis having a housing defining a chamber. The chamber includes: a first well region including at least one first well, the first well region configured to receive a test agent therein and further including biomolecules immobilized therein; a second well region including at least one second well, the second well region configured to receive a sample comprising cells therein and further being horizontally offset with respect to the first well region in a test orientation of the device; and a channel region with biomolecules immobilized therein and including at least one channel connecting the first well region and the second well region with one another. The method also includes forming a surface concentration gradient along a longitudinal axis of the chamber by decreasing the concentration of biomolecules from the at least one first well to the at least one second well; placing a first sample comprising cells in the at least one second well; and monitoring haptotaxis of the cells.
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申请公布号 |
US2003022153(A1) |
申请公布日期 |
2003.01.30 |
申请号 |
US20020097304 |
申请日期 |
2002.03.15 |
申请人 |
KIRK GREGORY;BROWN MATTHEW;OSTUNI EMANUELE;KIM ENOCH;AUMOND BERNARDO D.;SCHUELLER OLIVIER;SWEETNAM PAUL;BENOIT BRIAN |
发明人 |
KIRK GREGORY;BROWN MATTHEW;OSTUNI EMANUELE;KIM ENOCH;AUMOND BERNARDO D.;SCHUELLER OLIVIER;SWEETNAM PAUL;BENOIT BRIAN |
分类号 |
B01L3/00;C12M3/00;C40B40/06;C40B40/10;C40B60/14;G01N33/543;G06T7/00;(IPC1-7):C12Q1/00;C12M1/34 |
主分类号 |
B01L3/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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