| 摘要 |
This invention relates to a diagnostic methods of identifying an individual at an increased risk of breast carcinoma associated with a polymorphism in an MHC gene, by determining the genotypes of an individual and identifying polymorphisms associated with the predisposition or susceptibility to breast carcinoma. Also provided is a method of managing and treating patients with an increased risk or predisposition to breast carcinoma. The invention also provides to screening assays, and prophylactic and therapeutic methods discovered using such screening assays.
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