发明名称 |
METHOD FOR PREPARING 4-METHYLAMINO-4-PHENYLPIPERIDINE |
摘要 |
The invention concerns a method for preparing a 4-alkoxycarbonylamino-1-benzyl-4-phenylpiperidine of formula (I) by hydrolysis of 1-benzyl-4-cyano-4-phenylpiperidine (II) in acid medium and treatment of 1-benzyl-4-phenyl-4-piperidinecarboxamide (III) thus obtained with bromine in the presence of an alkaline alcoholate. The invention also concerns a method for preparing 4-methylamino-4-phenylpiperidine from said compound (II).
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申请公布号 |
WO03008381(A1) |
申请公布日期 |
2003.01.30 |
申请号 |
WO2002FR02498 |
申请日期 |
2002.07.15 |
申请人 |
SANOFI-SYNTHELABO;ANNE-ARCHARD, GILLES;GROS-CLAUDE, PATRICK |
发明人 |
ANNE-ARCHARD, GILLES;GROS-CLAUDE, PATRICK |
分类号 |
C07D211/58;(IPC1-7):C07D211/58 |
主分类号 |
C07D211/58 |
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