发明名称 |
Recombinant vector derived from adeno-associated virus for gene therapy |
摘要 |
<p>The present invention is related to a recombinant adeno-associated viral construct comprising at least: a first terminal repeat of an Adeno Associated Virus a strong heterologous promoter an heterologous DNA with at least 90% homology to the gene encoding for a constitutively activated TGF- beta 1 peptide, said gene being under the control of said promoter a polyadenylation signal a second terminal repeat of an Adeno Associated Virus <IMAGE></p> |
申请公布号 |
EP1279740(A1) |
申请公布日期 |
2003.01.29 |
申请号 |
EP20010870167 |
申请日期 |
2001.07.26 |
申请人 |
VRIJE UNIVERSITEIT BRUSSEL |
发明人 |
DE GREVE, JACQUES;TEUGELS, ERIK;NEYNS, BART;ZEINOUN, ZIAD;VERMEIJ, JOANNA |
分类号 |
A61K48/00;C07K14/495;C12N15/86;C12N15/864;(IPC1-7):C12N15/86;C12N5/16 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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