发明名称 |
IMIDAZOPYRIMIDINE DERIVATIVES AND TRIAZOLOPYRIMIDINE DERIVATIVES |
摘要 |
A compound of the formula (I) in which R<SUP>1 </SUP>is -OR<SUP>11</SUP>, -SR<SUP>11</SUP>, -SOR<SUP>11</SUP>, -SO<SUB>2</SUB>R<SUP>11</SUP>, -NHR<SUP>11</SUP>, or -NR<SUP>12</SUP>R<SUP>13 </SUP>, and R<SUP>11</SUP>, R<SUP>12</SUP>, and R<SUP>13 </SUP>are as defined broadly in the text. R<SUP>2 </SUP>is H, C<SUB>1</SUB>-C<SUB>6</SUB>alkyl, carbamoyl, or an ester group. R<SUP>3 </SUP>is thienyl, pyridyl optionally substituted by halogen or C<SUB>1</SUB>-C<SUB>6</SUB>alkoxy; naphthyl optionally substituted by C<SUB>1</SUB>-C<SUB>6</SUB>alkoxy; dioxane fused phenyl; dioxacyclopentane fused phenyl; or optionally substituted phenyl. Y is CH or N. A process for preparing such compounds, pharmaceutical compositions containing such compounds, and a method of treating asthma using them are also disclosed and claimed. |
申请公布号 |
EP1278750(A1) |
申请公布日期 |
2003.01.29 |
申请号 |
EP20010936242 |
申请日期 |
2001.04.17 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
YURA, TAKESHI;CONCEPCION, ARNEL B.;HAN, GYOONHEE;HIRAOKA, MAKIKO;KATSUMATA, HIROKO;KAWAMURA, NORIHIRO;KOKUBO, TOSHIO;KOMURA, HIROSHI;LI, YINGFU;LOWINGER, TIMOTHY B.;MOGI, MUNETO;YAMAMOTO, NORIYUKI;YOSHIDA, NAGAHIRO;WANG. MING |
分类号 |
A61K31/519;A61K31/5377;A61K31/541;A61P1/04;A61P3/04;A61P7/02;A61P7/06;A61P11/02;A61P11/06;A61P17/00;A61P17/04;A61P17/06;A61P19/02;A61P21/04;A61P25/28;A61P27/02;A61P27/14;A61P29/00;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D487/04;C07D519/00;(IPC1-7):C07D487/04;A61K31/505 |
主分类号 |
A61K31/519 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|