| 发明名称 |
Methods for designing exogenous regulatory molecules |
| 摘要 |
Methods for the design of exogenous regulatory molecules, comprising a DNA-binding domain and a functional domain, are provided. The methods rely on the identification, isolation and characterization of regulatory DNA sequences obtained on the basis of their accessibility in cellular chromatin.
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| 申请公布号 |
US6511808(B2) |
申请公布日期 |
2003.01.28 |
| 申请号 |
US20010844493 |
申请日期 |
2001.04.27 |
| 申请人 |
SANGAMO BIOSCIENCES, INC. |
发明人 |
WOLFFE ALAN;URNOV FYODOR;GUSCHIN DMITRY;COLLINGWOOD TREVOR;LI XIAO-YONG;JOHNSTONE BRIAN |
| 分类号 |
C07K14/47;C12N15/10;C12N15/62;C12N15/63;C12N15/66;C12Q1/68;G06F19/22;G06F19/28;(IPC1-7):C12Q1/68 |
主分类号 |
C07K14/47 |
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