发明名称 |
Process for the preparation of bicyclic compounds and the use of this process for the preparation of an ice inhibitor compound |
摘要 |
A method for preparing compounds of formula (I)wherein R is selected from the group consisting of H. alkyl, aryl, and aralkyl of up to 18 carbon atoms and the amine function may be free or protected from a compound of formula (IA) wherein cyclization is carried out in a basic medium and in the presence of a phosphonic acid derivative and the use of said method as an intermediate step for preparing a compound inhibiting the interleukin-1 beta conversion enzyme.
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申请公布号 |
US6512111(B1) |
申请公布日期 |
2003.01.28 |
申请号 |
US20010869950 |
申请日期 |
2001.07.27 |
申请人 |
AVENTIS PHARMA S.A. |
发明人 |
VERONIQUE CROCQ;ROUSSEL PATRICK |
分类号 |
C07D237/04;C07D487/04;C07K5/078;(IPC1-7):C07D237/04 |
主分类号 |
C07D237/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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