发明名称 |
High affinity human antibodies to tumor antigens |
摘要 |
This invention provides novel chimeric molecules that specifically binds a tumor cell bearing a c-erbB-2. The chimeric molecules comprise an effector molecule attached to a C6 antibody that specifically binds to c-erbB-2. The chimeric molecules can specifically target and deliver effector molecules to cells overexpressing c-erb-B2.
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申请公布号 |
US6512097(B1) |
申请公布日期 |
2003.01.28 |
申请号 |
US19990315574 |
申请日期 |
1999.05.20 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MARKS JAMES D.;SCHIER ROBERT |
分类号 |
A61K38/00;C07K16/32;C12P21/08;G01N33/574;(IPC1-7):C07K16/30;C07K16/46 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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