发明名称 PHENYL AND PYRIDYL TETRAHYDRO PYRIDINES HAVING TNF INHIBITING ACTIVITY.
摘要 <p>The invention concerns compounds of formula (I) wherein: X represents N or CH; R1 represents a hydrogen or halogen atom, or a CF3 group; R2 and R3 independently represent a hydrogen atom or a methyl group; n is 0 or 1; A represents a group of formula (a) or (b) wherein: R4 represents a hydrogen or halogen atom, a C1 C4 alkyl group, a CF3 group, an amino, mono(C1 C4)alkylamino, di(C1 C4)alkylamino; R5 represents a hydrogen or halogen atom, a (C1 C4)alkoxy group, a (C1 C4)alkyl group or a CF3 group; R6 represents a hydrogen atom, a (C1 C4)alkyl group or a (C1 C4)alkoxy group; and their salts or solvates, pharmaceutical compositions containing them, a method for preparing them and the synthesis intermediates in said method.</p>
申请公布号 MXPA02003979(A) 申请公布日期 2003.01.28
申请号 MX2002PA03979 申请日期 2000.10.19
申请人 SANOFI-SYNTHELABO 发明人 UMBERTO GUZZI
分类号 A61K;A61K31/4427;A61K31/47;A61K31/4709;A61K31/4725;A61P;A61P1/04;A61P3/10;A61P7/00;A61P9/00;A61P9/04;A61P9/10;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P19/08;A61P19/10;A61P25/00;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P33/06;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07D;C07D215/14;C07D217/02;C07D401/06;C07D401/14;(IPC1-7):A61K31/470;A61K31/472 主分类号 A61K
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