摘要 |
PROBLEM TO BE SOLVED: To obtain papilloma pseudo-virus which can be reached Peyer's patch, the proper mucous membrane and the spleen by oral administration, and with which stronger CTL reaction than a plasmid DNA vaccine can be induced by systemic immunization, and to provide a method for preparing the same. SOLUTION: The papilloma pseudo-virus comprises at least a papilloma virus-like particle and a plasmid enclosed in the papilloma virus-like particle. |