发明名称 TRIAZEPINONES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION
摘要 FIELD: organic chemistry, chemical technology, medicine, endocrinology, pharmacy. SUBSTANCE: invention describes novel derivatives of triazepinone of the general formula (I) where R means methyl group; R1 and R2 mean independently C1-8-alkyl; R3 and R4 mean hydrogen atom, their salts with pharmaceutically acceptable acids, method of their synthesis and pharmaceutical composition showing antiglycative effect. New compounds cane be used in diabetes mellitus treatment and associated complications. EFFECT: improved method of synthesis, valuable hypoglycemic property. 4 cl
申请公布号 RU2197483(C2) 申请公布日期 2003.01.27
申请号 RU20000120920 申请日期 1999.01.11
申请人 MERK PATENT GMBKH 发明人 RUGG'ERO DAN'EL';V'ERNSPERGER NIKOLA;PATERO ZHERAR;MUANE ZHERAR
分类号 C07D255/02;A61K;A61K31/41;A61K31/55;A61P3/10;A61P43/00;C07C;C07C255/02;C07D;(IPC1-7):C07D255/02 主分类号 C07D255/02
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