发明名称 |
PROCESS FOR PRODUCING ERYTHROMYCIN DERIVATIVE |
摘要 |
A method of introducing a 6-position substituent into a 6,9-cyclic acetal of a 5-O-desosaminylerythronolide derivative, characterized by cleaving the cycli c acetal selectively at the 9-position C-O bond; and a process for efficiently synthesizing a 6-O-substituted ketolide derivative which comprises a combination of conversion of each of the 9- and 3-position substituents into a carbonyl group and formation of a 11,12-cyclic carbamate.
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申请公布号 |
CA2417319(A1) |
申请公布日期 |
2003.01.27 |
申请号 |
CA20012417319 |
申请日期 |
2001.08.10 |
申请人 |
TAISHO PHARMACEUTICAL CO., LTD. |
发明人 |
KAMIYAMA, HIROAKI;KUWADA, TAKESHI;ADACHI, TAKASHI;SUZUKI, NOBUYUKI;KASHIMURA, MASATO |
分类号 |
C07H17/08;(IPC1-7):C07H17/08;C07H1/00 |
主分类号 |
C07H17/08 |
代理机构 |
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