PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL PREPARATION COMPRISING OXAPROZINE POTASSIUM, SODIUM AND TRIS SALTS, THEIR APPLICATION FOR PAIN RELIEF OR WEAKENING IN MAMMAL AND FOR TREATMENT OF INFLAMMATION AND DISORDERS ASSOCIATED WITH INFLAMMATION IN MAMMAL, METHOD OF PHARMACEUTICAL PREPARATION PREPARING

摘要

FIELD: medicine, pharmacy. SUBSTANCE: invention relates to pharmaceutical composition for oral use that produces the required therapeutic response in tablet, caplet or other pressed form comprising oxaprozine potassium, sodium or tris salt. Tablet, caplet or other pressed form of pharmaceutical composition becomes to be dissolved usually by about 75% in phosphate buffer medium for about 30 min. Composition can comprise suitable lubricating agent, suitable binding agent. Pharmaceutical composition provides relief or weakening of pain intensity in mammal and treatment of inflammation and disorders associated with inflammation, for example, rheumatic arthritis and osteoarthritis and related disorders and states in mammal. EFFECT: improved method of preparing, valuable medicinal properties of composition and preparation. 36 cl, 83 tbl