发明名称 APPLICATION OF ACID ALKYLFUMARATES FOR TREATMENT OF PSORIASIS, PSORIATIC ARTHRITIS, NEURODERMITIS AND CHRONIC CICATRIZING ENTERITIS (CROHN'S DISEASE)
摘要 FIELD: medicine, dermatology. SUBSTANCE: invention describes application of one or more acid alkylfumarates of the general formula (I): where R means C1-C5-alkyl mixed if necessary with dialkyl-fumarates of the formula (II): and, possibly, with conventional pharmaceutical accessory agents and carriers for preparing pharmaceutical preparative form as microtablets or microgranules. Proposed acid fumarates are used for treatment of psoriasis, psoriatic arthritis, neurodermitis and chronic cicatrizing enteritis. Microtablets and microgranules are distributed in stomach uniformly. EFFECT: improved and valuable medicinal properties of compounds. 7 cl, 2 tbl, 1 ex
申请公布号 RU2197233(C2) 申请公布日期 2003.01.27
申请号 RU20000127112 申请日期 1998.12.08
申请人 FUMAFARM AG 发明人 DZHOSHI RADZHENDRA K.;SHTREBEL' KHANS-PETER
分类号 A61K9/20;A61K9/50;A61K31/194;A61K31/22;A61K31/225;A61P17/00;A61P17/06;A61P19/02;A61P43/00;(IPC1-7):A61K31/194 主分类号 A61K9/20
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