| 摘要 |
PROBLEM TO BE SOLVED: To provide a method capable of dense accumulation of analyte in a solution and capable of simplified yet highly sensitive detection of the analyte, a device usable for this purpose, and an apparatus equipped with such a device. SOLUTION: The analyte measuring method contains a process for capturing the analyte at one or more regions on the substrate, a process for altering the geometry of the capturing region of the analyte, and a process for detecting the geometrical alteration to detect the presence of the analyte. The process of geometrical alteration is accomplished by supplying energy to the capturing region in the presence of a labelling substance that specifically connects to the analyte captured in the substrate. The labelling substrate may be a shading substance or a photo-curing resin, and the energy is selected from the group consisting of visible rays, ultraviolet rays, infrared rays, X-rays, and electron beams.
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