| 摘要 |
PURPOSE: A composition containing lysophosphatidic acid and a pharmaceutically acceptable salt as an effective ingredient is provided which can be effectively used for prevention and treatment of cerebral apoplexy by remarkably lowering brain infarction by brain ischemia. CONSTITUTION: The composition contains lysophosphatidic acid of formula 1 and a pharmaceutically acceptable salt, wherein R1 is substituted or non-substituted linear or branched C4-30 alkyl. The pharmaceutically acceptable salt of lysophosphatidic acid is, for example, an inorganic salt such as a sodium salt, magnesium salt and calcium salt, and organic salt such as ammonium salt, lysin, ethanolamine, N,N'-dibenzylethylene amine, angelic acid, but it is not limited within them.
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