COMBINATION OF CHIPS (CHEMOTAXIS INHIBITING PROTEIN FROM STAPHYLOCOCCUS AUREUS)-BASED COMPOUNDS

摘要

The invention relates to a combination of compounds, wherein one compound has CHIPS activity and consists of at least 6 building blocks the sequence of which is based on the N-terminal part of the CHIPS molecule, and which sequence may comprise one or more substitutions as compared to the original CHIPS amino acid sequence, whereas the one or more other compounds are derived from the aminoa cids 4-121 of CHIPS and supports CHIPS activity. One or more of the amino acids in the amino acid sequence of the one or more supportive compounds may be replaced by building blocks selected from the group consisting of proteinogenic amino acids, non-proteinogenic amino acids, D-amino acids and peptidomimetic building blocks.