发明名称 |
Mono-specific polyclonal antibodies and methods for detecting Clostridium difficile Toxin A |
摘要 |
A method is provided for the purification of Clostridium difficile Toxin A antigen comprising reacting impure Toxin A with immobilized mono-specific polyclonal antibodies. The polyclonal antibodies are coupled to a hydrazide group containing matrix such as hydrazide activated agarose gel. The immobilized antibody is specific for Toxin A and will greatly purify Toxin A from a Toxin A containing solution. Antibodies raised to Toxin A purified according to the method are of higher activity than antibodies produced from prior art purified Toxin A.
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申请公布号 |
US2003018170(A1) |
申请公布日期 |
2003.01.23 |
申请号 |
US20020224752 |
申请日期 |
2002.08.20 |
申请人 |
DEUTSCH JOHN WILLIAM |
发明人 |
DEUTSCH JOHN WILLIAM |
分类号 |
C07K16/12;C12P21/02;(IPC1-7):C07K1/00;C07K14/00;C07K17/00 |
主分类号 |
C07K16/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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