| 发明名称 |
PROTEIN DESIGN AUTOMATION FOR DESIGNING PROTEIN LIBRARIES WITH ALTERED IMMUNOGENICITY |
| 摘要 |
The present invention relates to the use of a variety of computational methods for modulating the immunogenicity of proteins by identifying and then altering potential amino acid sequences that elicit an immune response in a host organism. In particular, proteins will be screened for MHC binding sequences, T cell epitopes and B cell epitopes. |
| 申请公布号 |
WO03006154(A2) |
申请公布日期 |
2003.01.23 |
| 申请号 |
WO2002US00165 |
申请日期 |
2002.01.04 |
| 申请人 |
XENCOR, INC. |
发明人 |
CHIRINO, ARTHUR;DAHIYAT, BASSIL, I.;DESJARLAIS, JOHN |
| 分类号 |
C07K1/00;C07K1/04;C07K14/47;C07K14/765 |
主分类号 |
C07K1/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
