摘要 |
<p>Analgesic basic furanone derivs. Title cpds. are of formula (I): (where R1 is H or lower alkyl; R2 is H, F, Cl, Br, lower alkyl or alkoxy, or NHCOR3 where R3 is lower alkyl). Specific cpds. are 3- 1-(4-m-fluorophenyl-4-oxo-butyl)-4-hydroxy-4-piperidyl dihydro- -2(3H)-furanone, dihydro-3- 4-hydroxy-1-(4-oxo-4-o-tolyl-butyl)-4-piperidyl dihydr- o-2(3H)-furanone, etc.</p> |