发明名称 L−ASCORBIC ACID−2−O−MALEIC ACID−A−TOCOPHEROL DIESTER 1−PROPANOL ADDUCT AND PROCESS FOR PRODUCING THE SAME
摘要 L−Ascorbic acid−2−o−maleic acid−&agr;−tocopherol diester 1−propanol adduct or its pharmacologically acceptable salt; cosmetic components, antioxidants, radical scavengers, antiinflammatory agents and elastase inhibitors containing the same as the active ingredient; and a process for producing the above−described adduct characterized by comprising extracting a solution containing L−ascorbic acid−2−o−maleic acid−&agr;−tocopherol diester with a solvent, distilling off the solvent and adding to the residue 1−propanol optionally mixed with an organic solvent followed by crystallization.
申请公布号 WO03006460(A1) 申请公布日期 2003.01.23
申请号 WO2002JP05573 申请日期 2002.06.05
申请人 SENJU PHARMACEUTICAL CO., LTD.;OGATA, KAZUMI;SAITO, NORIKO;YAMADA, KAZUHIKO;MARUYAMA, GENTA 发明人 OGATA, KAZUMI;SAITO, NORIKO;YAMADA, KAZUHIKO;MARUYAMA, GENTA
分类号 A61K8/49;A61P17/16;A61P29/00;A61P39/06;A61P43/00;C07D407/12;C07H19/23;(IPC1-7):C07D407/12;A61K7/00 主分类号 A61K8/49
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