SYNTHESIS, METHODS OF USING, AND COMPOSITIONS OF HYDROXYLATED CYCLOBUTYLALKYLAMINES

摘要

The invention realtes, in part, to making of making and using, and compositions comprising, racemic and stereomerically pure cyclobutylalkylamines, including hydroxylated sibutramine and hydroxylated metabilites of sibutramine. Methods of treating and preventing a variety of diseases and disorders are disclosed, as are pharmeaceutical compositions and unit dosage forms that comprise compounds of the invention.