INHIBITORS OF HIV REPLICATION AND METHOD OF TREATMENT OF HIV INFECTIONS

摘要

The invention is drawn to a novel class of drugs directed against HIV, comprising a peptide or analog comprising a decapeptide, said decapeptide containing (from N-terminus to the C-terminus) a basic amino acid in position (1), an acidic amino acid in positions (2 and 5), and a tryptophan in positions (4, 7 and 8), and to a method of treatment of HIV infections, in particular multidrug-resistant HIV infections.