| 发明名称 |
A THYMUS EXPRESSED HUMAN CYTOCHROME P450 (P450TEC) |
| 摘要 |
The present invention relates to a novel human gene encoding a polypeptide that is a member of the cytochrome P450 family. More specifically, the present invention relates to a polynucleotide encoding a novel human polypeptide named cytochrome P450TEC (Thymus Expressed Cytochrome). This invention also relates to P450TEC polypeptides, as well as vectors, host cells, and antibodies directed to P450TEC polypeptides, and the recombinant methods for producing the same. Also provided are therapeutic methods for treating P450TEC-related disorders. The invention further relates to screening methods for identifying agonists and antagonists of P450TEC activity. |
| 申请公布号 |
EP1276872(A2) |
申请公布日期 |
2003.01.22 |
| 申请号 |
EP20010923443 |
申请日期 |
2001.04.20 |
| 申请人 |
CYTOCHROMA INC. |
发明人 |
JONES, GLENVILLE;PETKOVICH, P., MARTIN;WHITE, JAY, A.;RAMSHAW, HEATHER, A.;STANGLE, WAYNE, A. |
| 分类号 |
C12N15/09;A61K31/7088;A61K38/00;A61K38/43;A61K39/395;A61K45/00;A61K48/00;A61P1/00;A61P3/10;A61P5/00;A61P5/14;A61P7/00;A61P7/04;A61P7/06;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P19/02;A61P21/04;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P39/02;A61P43/00;C07K14/80;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/02;C12N15/53;C12Q1/26;C12Q1/68 |
主分类号 |
C12N15/09 |
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