| 摘要 |
<p>The present invention relates to a method for preparing 5- and 6-halomethyl quinoxalines. The method comprises contacting a 5- or 6-methyl quinoxaline with a halogenating agent in the presence of a radical initiator in a solvent selected from the group consisting of fluorobenzene, difluorobenzenes, trifluorobenzenes, chlorobenzene, dichlorobenzenes, trichlorobenzenes, α, α, α-trifluorotoluene and α, α, α-trichlorotoluene. The method for halogenating benzylic methyl groups may also be employed to halogenate a wide variety of halomethyl heterocyclic compounds.
<Chemistry id="chema01" num="0001"><Image id="ia01" he="24" wi="79" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry></p> |
