发明名称 |
Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof |
摘要 |
The present invention provides a novel sustained release composition and method for making such a composition of diclofenac and its pharmaceutically acceptable salts. The composition of the present invention provides a sustained release formulation of diclofenac and pharmaceutically acceptable salts thereof which is suitable for once daily administration and provides controlled and long lasting in vivo release. The composition comprises: (a) about 5-25% by weight of hydroxyethyl cellulose; (b) about 5-75% by weight of lactose; (c) about 0-3% by weight of silicone dioxide; (d) about 0.5-5% by weight of PVP; (e) about <3% by weight of talc; and f) about <3% by weight of magnesium stearate.
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申请公布号 |
US6509037(B2) |
申请公布日期 |
2003.01.21 |
申请号 |
US20010945056 |
申请日期 |
2001.08.31 |
申请人 |
ODIDI ISA;ODIDI AMINA |
发明人 |
ODIDI ISA;ODIDI AMINA |
分类号 |
A61K9/20;A61K9/22;A61K31/196;(IPC1-7):A61K9/16 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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