发明名称 |
Process for the removal of a silyloxy protecting group from 4-silyloxy-tetrahydro-pyran-2-ones |
摘要 |
This invention relates to a novel method for the removal of a silyl protecting group from the 4-hydroxy group of tetrahydropyran-2-ones, which method is particularly suitable in the process for the preparation of simvastatin and derivatives and analogs thereof.
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申请公布号 |
US6509479(B1) |
申请公布日期 |
2003.01.21 |
申请号 |
US20010869372 |
申请日期 |
2001.09.21 |
申请人 |
LEK PHARMACEUTICALS D.D. |
发明人 |
ZLICAR MARKO;RUCMAN RUDOLF |
分类号 |
C07D309/30;(IPC1-7):C07D309/30 |
主分类号 |
C07D309/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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