发明名称 Arylsulfonyl Hydroxamic Acid derivatives as MMP and TNF inhibitors
摘要 A compound of the formulawherein R1-R9 and Ar are as defined above, useful in the treatment of a condition selected from the group consisting of arthritis, cancer, tissue ulceration, restenosis, periodontal disease, epidemrolysis bullosa, scleritis and other disease characterized by matrix metalloproteinase activity, as well as AIDS, sepsis, septic shock and other diseases involving the production of TNF.
申请公布号 US6509337(B1) 申请公布日期 2003.01.21
申请号 US19980154969 申请日期 1998.09.17
申请人 PFIZER INC. 发明人 PISCOPIO ANTHONY;RIZZI JAMES P.
分类号 A61K31/4965;A61K31/54;C07D211/96;C07D241/04;C07D265/30;(IPC1-7):A61K31/445;A61K31/496 主分类号 A61K31/4965
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