发明名称 AGENT FOR INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) AND CYTOMEGALOVIRUS (CMV) INFECTIONS AND METHOD OF THEIR INHIBITION
摘要 FIELD: medicine. SUBSTANCE: invention relates to etiotropic chemotherapy of viral infections, in part, agent used for inhibition of HIV and CMV infections and method of their inhibition. Method involves application of amino acid and dipeptide derivatives of fullerene of the general formula C60-X where C60 means fullerene nucleus; X means NH-CHR-COOH, NH-(CH2)n-COOH, NH-CHR-CO-NH-CHR-COOH where n = 2-6; R means by-side radical of natural amino acid or dipeptide as agent for inhibition of viral infections, in part, HIV and CMV infections. Method of application of water-soluble amino acid or dipeptide derivatives of fullerene of the general formula C60'-X as agent for inhibition of viral infections involves its effect on infected cellular cultures in vitro with effective inhibitory dose. EFFECT: enhanced inhibitory activity of agent. 20 cl, 1 tbl
申请公布号 RU2196602(C1) 申请公布日期 2003.01.20
申请号 RU20020101294 申请日期 2002.01.22
申请人 ZAKRYTOE AKTSIONERNOE OBSHCHESTVO "DESKO" 发明人 MILLER G.G.;KUSHCH A.A.;ROMANOVA V.S.
分类号 A61K38/05;A61K38/55;(IPC1-7):A61K38/05 主分类号 A61K38/05
代理机构 代理人
主权项
地址