发明名称 |
METHOD OF PREPARING R-TETRAOL ELICITING ANTITUMOR ACTIVITY |
摘要 |
FIELD: chemistry, pharmacology. ! SUBSTANCE: active component is isolated from natural product. Galipot of coniferous strains of species Pinus sibirica and/or Pinus cembra, and/or of genus Abies, and/or of genus Larix are used as natural product and labdanoido-diterpenic acids are isolated followed by camphor addition to isolated fraction and effect on prepared mixture by gamma-radiation up to formation of R-tetraol structure. Invention can be used for antitumor preparation preparing. ! EFFECT: improved method of preparing, decreased cost of product. 1 tbl, 5 dwg |
申请公布号 |
RU2196581(C2) |
申请公布日期 |
2003.01.20 |
申请号 |
RU20000110788 |
申请日期 |
2000.05.04 |
申请人 |
KOLESNIKOV ANDREJ GRIGOR'EVICH;REMIZOVA OL'GA VIKTOROVNA;ZHIGUNOVA LARISA NIKOLAEVNA;LUKASHEVICH EHMILIJA ADOL'FOVNA |
发明人 |
REMIZOVA O.V.;ZHIGUNOVA LARISA NIKOLAEVNA;ZHIGUNOV DIONIS IGOREVICH;MASHEVSKIJ ALEKSANDR AL'FREDOVICH;ZHAVRID EHDVARD BORISOVICH |
分类号 |
A61K41/00;A61K;A61K31/337;A61K36/00;A61K36/15;A61K129/00;A61P35/00;C07D305/14 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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