| 发明名称 |
Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases |
| 摘要 |
The present invention provides compounds, and pharmaceutical compositions containing those compounds, that are active at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
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| 申请公布号 |
US2003013715(A1) |
申请公布日期 |
2003.01.16 |
| 申请号 |
US20020211523 |
申请日期 |
2002.08.05 |
| 申请人 |
NPS PHARMACEUTICALS, INC. |
发明人 |
VAN WAGENEN BRADFORD C.;MOE SCOTT T.;SMITH DARYL L.;SHEEHAN SUSAN M.;SHCHERBAKOVA IRINA;WALTON RUTH;TROVATO RICHARD;BARMORE ROBERT;DELMAR ERIC G.;STORMANN THOMAS M. |
| 分类号 |
C07D209/42;C07D213/81;C07D213/82;C07D215/12;C07D215/20;C07D215/38;C07D215/48;C07D215/54;C07D217/26;C07D241/42;C07D241/44;C07D277/68;C07D277/70;C07D307/68;C07D307/84;C07D333/38;C07D333/68;C07D491/04;C07D521/00;(IPC1-7):A61K31/495;A61K31/50;A61K31/52 |
主分类号 |
C07D209/42 |
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