发明名称 |
High affinity humanized anti-TAG-72 monoclonalantibodies |
摘要 |
Novel humanized monoclonal antibodies, humanized antibody fragments, and derivatives thereof which specifically bind TAG-72 are provided as well as methods for their manufacture. These humanized antibodies are useful in the treatment of cancers which express TAG-72 as well as for diagnostic purposes, e.g., for in vivo imaging of tumors or cancer cells which express TAG-72.
|
申请公布号 |
US2003013856(A1) |
申请公布日期 |
2003.01.16 |
申请号 |
US20010040997 |
申请日期 |
2001.10.31 |
申请人 |
ANDERSON W.H. KERR;TEMPEST PHILIP R.;CARR FRANK J.;HARRIS WILLIAM J.;ARMOUR KATHRYN |
发明人 |
ANDERSON W.H. KERR;TEMPEST PHILIP R.;CARR FRANK J.;HARRIS WILLIAM J.;ARMOUR KATHRYN |
分类号 |
C07K16/30;(IPC1-7):A61K51/00;G01N33/574;A61K39/395;C07K16/46 |
主分类号 |
C07K16/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|