| 发明名称 |
THIAZOLE BENZAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING CELL PROLIFERATION, AND METHODS FOR THEIR USE |
| 摘要 |
Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutical ly acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutical ly acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and ar e useful as pharmaceuticals for treating malignancies and other disorders.</SD OAB>
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| 申请公布号 |
CA2452609(A1) |
申请公布日期 |
2003.01.16 |
| 申请号 |
CA20022452609 |
申请日期 |
2002.07.05 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC |
发明人 |
ROMINES, WILLIAM H.;DUVADIE, ROHIT K.;WALLACE, MICHAEL B.;REICH, SIEGFRIED H.;LI, LIN;YANG, YI;CHONG, WESLEY K. M.;BLECKMAN, TED MICHAEL;ALEGRIA, LARRY ANDREW;CHU, SHAO SONG |
| 分类号 |
C07D277/62;A61K31/426;A61K31/427;A61K31/428;A61K31/438;A61K31/4439;A61K31/454;A61K31/4709;A61K31/4725;A61K31/496;A61K31/506;A61K31/5377;A61K31/541;A61P1/04;A61P1/16;A61P3/10;A61P7/06;A61P9/00;A61P9/06;A61P9/10;A61P11/00;A61P13/08;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P21/00;A61P25/00;A61P25/04;A61P25/16;A61P25/28;A61P27/02;A61P27/16;A61P29/02;A61P31/10;A61P31/12;A61P31/14;A61P31/18;A61P31/20;A61P31/22;A61P35/00;A61P35/02;A61P35/04;A61P37/00;A61P37/02;A61P37/04;A61P37/06;A61P43/00;C07D277/20;C07D277/38;C07D277/42;C07D277/44;C07D277/56;C07D417/06;C07D417/12;C07D417/14;C07D491/10;C07D491/20;C07D521/00;(IPC1-7):C07D417/12;A61P33/00;C07D413/12;A61K31/416;A61K31/417;A61K31/537 |
主分类号 |
C07D277/62 |
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