METHOD FOR INCREASING HYDROPHILICITY OF FLUORESCENT LABEL COMPOUNDS

摘要

The invention relates to fluorescent label compounds of formula or , wherein Z is a reactive group that can be used for covalent coupling of the fluorescent label compound to other molecules. Either the fluorophore is a dipyrrometheneboron difluoride dye and Y is a water-solubilizing moiety, or Y is -CH2CH2SO3<->X<+> where X<+> is a cation. The invention also relates to the use of the compounds in bioanalytical assays and cytological or histological staining methods. The invention further relates to a method for increasing the hydrophilicity of fluorescent compounds.