摘要 |
A device for detecting molecular binding events rapidly and at very high sensitivity is provided. The device molecular binding material (such as DNA or protein) positioned in a conductive path between electrodes. Binding of a ligand to the binding material is detected as a change in a frequency response in applied oscillatory field. The device may also contain an optical measurement system (based, for example, on a laser) which detects the change in thickness of the molecular binding material under an applied oscillatory field with and without a bound material of interest.
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