NOVEL AMINOPEPTIDASE DERIVED FROM BACILLUS LICHENIFORMIS, GENE ENCODING THE AMINOPEPTIDASE, EXPRESSION VECTOR CONTAINING THE GENE, TRANSFORMANT AND METHOD FOR PREPARATION THEREOF

摘要

The present invention relates to novel aminopeptidase derived from Bacillus licheniformis, a gene encoding the aminopeptidase, an expression vector containing the gene, a cell transformant transfected with the expression vector and a process for preparing a natural type protein using thereof. Mor e particularly, the present invention relates to a gene encoding aminopeptidas e which is cloned and manufactured using the recombinant DNA technique, an expression vector containing the gene, a cell transformant transfected with the expression vector and a recombinant aminopeptidase which is necessary to produce recombinant human growth hormone in a natural type protein and can b e expressed in a high yield more stably and advantageously, compared with conventional methods for the purification.