发明名称 Piperazinyl-isatins
摘要 This invention provides compounds of formula VI wherein Y is hydrogen, methyl, methoxy, methylthio or trifluoromethyl; R is hydrogen, C1-3alkyl or (CH2)nAr; n is 0, 1 or 2; and Ar is phenyl or methoxyphenyl, or a pharmaceutically acceptable salt thereof. These compounds are selective dopamine autoreceptor agonists useful in treating disease states involving hyperactivity of dopamine systems. The invention also comprises intermediate compounds, compositions and methods related to the compounds of formula VI.
申请公布号 US2003013722(A1) 申请公布日期 2003.01.16
申请号 US20020139695 申请日期 2002.05.03
申请人 WYETH 发明人 GREENBLATT LYNNE P.;JIRKOVSKY IVO;MEWSHAW RICHARD E.
分类号 C07D209/38;C07D295/073;C07D295/135;C07D295/155;(IPC1-7):A61K31/496;C0743/02 主分类号 C07D209/38
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