发明名称 Preparing 2,4-dideoxyhexose/2,4,6-trideoxyhexose by reacting optionally substituted carbonyl compound with alpha-hydrogen atom and two carbon atoms and optionally substituted aldehyde at specific carbonyl concentration
摘要 Preparing (M) 2,4-dideoxyhexose/2,4,6-trideoxyhexose (I), comprising reacting an optionally substituted carbonyl compound with at least 2 carbon atoms and at least one alpha-hydrogen atom and an optionally substituted aldehyde in the presence of aldolase and water, at a carbonyl concentration of at most 6 moles/l of reaction mixture, is new. Preparing (M) 2,4-dideoxyhexose/2,4,6-trideoxyhexose (I), comprising reacting an optionally substituted carbonyl compound with at least 2 carbon atoms and at least one alpha-hydrogen atom and an optionally substituted aldehyde in the presence of aldolase and water, at a carbonyl concentration of at most 6 moles/l of reaction mixture, is new. The final concentration of (I) is at least 2 mass% of the reaction mixture. An Independent claim is also included for use of 2,4-dideoxyhexose/2,4,6-trideoxyhexose (I), obtained by (I), in the preparation of a medicine.
申请公布号 NL1018525(C2) 申请公布日期 2003.01.16
申请号 NL20011018525 申请日期 2001.07.12
申请人 DSM N.V. 发明人 JOANNES GERARDUS THEODORUS KIERKELS;DANIEL MINK;SVEN PANKE;FRANCISCUS ALPHONS MARIE LOMMEN;DENNIS HEEMSKERK
分类号 C12N9/88;C12P19/02 主分类号 C12N9/88
代理机构 代理人
主权项
地址