发明名称 Alkali metal salt of thiazolidine-2,4-dione derivative
摘要 The invention provides alkali metal salt of 5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]benzamide and its hydrate. A method has been found, wherein, upon preparing KRP-297, the alkali metal salt of KRP-297 and its hydrate are formed in the reaction system and, after separation and purification, they are freed again from salt, thereby KRP-297 can be advantageously purified industrially for preparation.
申请公布号 US2003013749(A1) 申请公布日期 2003.01.16
申请号 US20020181432 申请日期 2002.07.25
申请人 OHNOTA MICHIRO;ORITA KAZUO;YOSHIDA NORIYUKI 发明人 OHNOTA MICHIRO;ORITA KAZUO;YOSHIDA NORIYUKI
分类号 C07D277/34;(IPC1-7):A61K31/426;C07D277/36 主分类号 C07D277/34
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