| 摘要 |
<p>Mutations in selected genes, such as the Frizzled-4 gene ('fzd4'), which are causative agents in hereditary human visual disorders, such as familial exudative vitreoretinopathy ('FEVR'), are disclosed along with methods of use, including assays for therapeutic agents useful in treating such diseases and/or ameliorating their effects as well as methods of diagnosing conditions of visual impairment caused by mutations in these genes.</p> |
