| 发明名称 |
Recombinant alpha-L-iduronidase, methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof |
| 摘要 |
The present invention provides a recombinant alpha-L-iduronidase and biologically active fragments and mutants thereof, methods to produce and purify this enzyme as well as methods to treat certain genetic disorders including-alpha-L-iduronidase deficiency and mucopolysaccharidosis I (MPS 1).
|
| 申请公布号 |
US2003013179(A1) |
申请公布日期 |
2003.01.16 |
| 申请号 |
US20020206443 |
申请日期 |
2002.07.25 |
| 申请人 |
KAKKIS EMIL D.;TANAMACHI BECKY |
发明人 |
KAKKIS EMIL D.;TANAMACHI BECKY |
| 分类号 |
C12N15/09;A61K9/08;A61K38/00;A61K38/43;A61K38/47;A61K47/02;A61K47/10;A61K48/00;A61P3/00;A61P19/00;A61P43/00;C12N9/24;C12N9/88;(IPC1-7):C12N9/24;C07H21/04;C12P21/02;C12N5/06 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
